HCG BASIC INFORMATION
HCG is used medically to positively influence ovulation in women, and to help produce estrogen. It is also utilized in fertility medicine to aid in ovulation. Male bodybuilders used HCG for another important reason. It is almost exactly the same amino acid sequence as Luteinizing Hormone (LH). LH is normally produced in the pituitary gland which is then circulated to the testes where it contacts the Leydig cells. The Leydig cells then produce androgens such as testosterone. Obviously this means so-called natural bodybuilders reported use of HCG to increase endogenous (natural) testosterone levels. According to some clinical studies this works so well that an injection of 1500-2000 i.u. of HCG has increased plasma testosterone levels 200-300% over normal levels. For those males who utilized high aromatizing AAS, HCG was a “partial” cure for restarting natural testosterone production either mid or post-cycles.
When 2000-5000 i.u. was injected every 5th day for 2-3 weeks, mid or post-cycle, the testes began to function again. Also an increase in total testosterone was realized and athletes often made some of their best gains at this point. It also helped to keep the “significant other” significantly happy! When HCG was administered beginning the last week of an AAS cycle and for an additional 1-2 weeks post-cycle, testes function normalized again and much of the common post- AAS cycle muscle mass and strength loss was avoided. However, our athletes were not out of the woods (with acceptable wood) quite yet. Earlier, I mentioned that it has been a utilized as a “partial cure” for the shut-down of the hypothalamus-pituitary-testes-axis (HPTA). HCG only “replaces” natural LH. The pituitary and hypothalamus part of the HPTA still sense no reason to produce gonadotropins and restore normal LH/FSH production. So ending HCG administration sometimes only brought on another crash. But staying on HCG for more than 3 weeks without at least a month off between HCG cycles could cause permanent gonadal dysfunction and/or a desensitizing of Leydig Cells. Male bodybuilders commonly used Clomid or Cyclofenil with HCG (*See Clomid for more info). Available literature shows that Clomid stimulates the pituitary to release more gonadotropin so a quicker and elevated level of LH and FSH are realized. By following an AAS cycle with 2000-5000 i.u. every 5th day for 2-3 weeks and ingesting Clomid for the last 10-15 days of administration many athletes noted that muscle mass and strength losses post AAS cycle were significantly avoided. Many athletes also used Clenbuterol at this point. (*See Clenbuterol for more info)